Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli
Abstract
Live chimeras between two species of mouse, Mus musculus and Mus caroli, were produced by blastocyst injection. These chimeras were entirely similar to M. musculus ↔ M. musculus chimeras in their somatic tissue organization. This is the first report of completely normal development of interspecific chimeras in mammals.
References
CHAPMAN, V.M., EXPRESSION OF PATERNAL GLUCOSE PHOSPHATE ISOMERASE-1 (GPI-1) IN PREIMPLANTATION STAGES OF MOUSE EMBRYOS, DEVELOPMENTAL BIOLOGY 26: 153 (1971).
CONDAMINE, H, GENE CONTROLE OF NEOPLASIA .2. PURE-STRAIN AND GENETICALLY MOSAIC LIVER TUMORS HISTOCHEMICALLY IDENTIFIED WITH BETA-GLUCURONIDASE MARKER IN ALLOPHENIC MICE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 68: 2032 (1971).
DEWEY, M.J., BRAIN AND GANGLION DEVELOPMENT FROM 2 GENOTYPIC CLASSES OF CELLS IN ALLOPHENIC MICE, DEVELOPMENTAL BIOLOGY 50: 68 (1976).
FALCONER, D.S., VARIABILITY OF CHIMAERAS AND MOSAICS, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 43: 195 (1978).
FORD, C.E., MARKER CHROMOSOME ANALYSIS OF 2 MOUSE CHIMAERAS, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 33: 447 (1975).
Frels, W. I., Journal of Reproduction and Fertility 59: 387 (1980).
GARDNER, R.L., CIBA F SYMP 29: 183 (1975).
GARDNER, R.L., EARLY DEV MAMMALS: 107 (1975).
GARDNER, R.L., INVESTIGATION OF EARLY MAMMALIAN DEVELOPMENT USING INTERSPECIFIC CHIMAERAS BETWEEN RAT AND MOUSE, NATURE-NEW BIOLOGY 246: 86 (1973).
HARRISON, R.G., ORG DEV EMBRYO: 215 (1969).
LEDOUARIN, N, DEV BIOL 30: 217 (1973).
MARSHALL, J.T., MAMMALIAN CHROMOSOMES NEWSLETTER 13: 13 (1972).
MAYER, T.C., MESODERM-ECTODERM INTERACTION IN PRODUCTION OF AGOUTI PIGMENTATION PATTERN IN MICE, GENETICS 71: 297 (1972).
MCLAREN, A, MAMMALIAN CHIMAERAS (1976).
MINTZ, B, GENE CONTROL OF MAMMALIAN PIGMENTARY DIFFERENTIATION .I. CLONAL ORIGIN OF MELANOCYTES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 58: 344 (1967).
MINTZ, B, NORMAL MAMMALIAN MUSCLE DIFFERENTIATION AND GENE CONTROL OF ISOCITRATE DEHYDROGENASE SYNTHESIS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 58: 592 (1967).
MORIWAKI, K, ANN REP NAT I GENET 28: 28 (1977).
MULNARD, J.G., FORMATION OF CHIMERIC BLASTOCYSTS BY FUSION OF RAT AND MOUSE EMBRYOS IN STAGE 8, COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE D 276: 379 (1973).
MYSTKOWSKA, E.T., DEVELOPMENT OF MOUSE-BANK VOLE INTERSPECIFIC CHIMAERIC EMBRYOS, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 33: 731 (1975).
PETERSON, A.C., TECHNIQUE FOR DETECTION AND RELATIVE QUANTITATIVE-ANALYSIS OF GLUCOSEPHOSPHATE ISOMERASE ISOZYMES FROM NANOGRAM TISSUE SAMPLES, BIOCHEMICAL GENETICS 16: 681 (1978).
ROSSANT, J, CONCEPTS MAMMALIAN E: 1 (1977).
ROSSANT, J, INVESTIGATION OF INNER CELL MASS DETERMINATION BY AGGREGATION OF ISOLATED RAT INNER CELL MASSES WITH MOUSE MORULAE, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 36: 163 (1976).
SOLTER, D, IMMUNO-SURGERY OF MOUSE BLASTOCYST, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 72: 5099 (1975).
STERN, M.S., NATURE 243: 472 (1973).
SUTTON, W.D., RELATED SATELLITE DNAS IN GENUS MUS, JOURNAL OF MOLECULAR BIOLOGY 71: 633 (1972).
WEST, J.D., DEVELOPMENT OF INTERSPECIFIC HYBRIDS OF MUS, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 41: 233 (1977).
WEST, J.D., MUS-MUSCULUS BY MUS-CAROLI HYBRIDS - MOUSE MULES, JOURNAL OF HEREDITY 69: 321 (1978).
ZEILMAKER, G.H., FUSION OF RAT AND MOUSE MORULAE AND FORMATION OF CHIMAERIC BLASTOCYSTS, NATURE 242: 115 (1973).
Get full access to this article
View all available purchase options and get full access to this article.
Already a Subscriber?Sign In
Information & Authors
Information
Published In
Science
Volume 208 • Issue 4442 • 25 April 1980
Pages: 419 - 421
History
Published online: 25 April 1980
Copyright
© 1980.
