Science Immunology
- Volume 7
- Issue 67
- 07 Jan 2022
ONLINE COVER Trail Markers for Tissue Macrophages. This month's cover illustration depicts a trail marker post in a desert landscape that provides a guide to deciphering the diversity among mouse and human tissue-resident macrophages. The trio of phenotypes (TLF+, CCR2+ and MHC-II+) listed on the post represent three conserved macrophage subsets defined by Dick et al. These subsets share common core gene signatures and life cycles across 17 different mouse tissues.
Credit: Ella Maru StudioResearch ArticlesBy
- Sarah A. Dick
- Anthony Wong
- et al.
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles
Research ArticlesBy
- Diyuan Xue
- Benjamin Moon
- et al.
A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors
Research ResourceBy
- Yannick O. Alexandre
- Dominik Schienstock
- et al.
A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity
ReviewsBy
- Søren R. Paludan
- Trine H. Mogensen
- et al.
Innate immunological pathways in COVID-19 pathogenesis
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Science Immunology publishes original, peer-reviewed, science-based research articles that report critical advances in all areas of immunological research, including important new tools and techniques.
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