Advertisement
Allegations of research misconduct were made about the Research Article “The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor” by T. M. Brand, M. Iida, K. L. Corrigan, C. M. Braverman, J. P. Coan, B. G. Flanigan, A. P. Stein, R. Salgia, J. Rolff, R. J. Kimple, D. L. Wheeler, published in Science Signaling on 3 January 2017 (1). After an investigation by the Office of the Vice Chancellor for Research and Graduate Education, University of Wisconsin-Madison, the investigating committee found that that various data in Figs. 1A, 1B, 2A, 2C, 2E, 4B, 5D, 6A, and 6C, as well as in figs. S2B and S4 were duplicated, mislabeled, or had other anomalies. The committee found that these issues were due to carelessness and lack of attention to detail rather than through any intent to deceive, and thus concluded that no research misconduct was committed. During the course of the investigation, it was discovered that whereas many of the figures could be updated with the original data, in some cases, the original data could not be identified. Thus, a complete correction of the record is not possible. Although it was determined by the investigating committee that these issues likely did not affect the overall conclusions of the study, the authors have requested that the paper be retracted in full to preserve the integrity of the scientific literature. The author Jana Rolff could not be contacted. The other authors of the Research Article have confirmed to the Editor of Science Signaling that they all concur with the retraction and apologize to the scientific community for any inconvenience caused. The Editor apologized for the delay in acting on this matter.

Reference

1
T. M. Brand, M. Iida, K. L. Corrigan, C. M. Braverman, J. P. Coan, B. G. Flanigan, A. P. Stein, R. Salgia, J. Rolff, R. J. Kimple, D. L. Wheeler, The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor. Sci. Signal. 10, eaag1064 (2017).

Information & Authors

Information

Published In

Science Signaling
Volume 14Issue 7089 November 2021
PubMed: 34752142

History

Published online: 9 November 2021

Permissions

Request permissions for this article.

Authors

Affiliations

Toni M. Brand
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Kelsey L. Corrigan
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Cara M. Braverman
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
John P. Coan
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Bailey G. Flanigan
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Ravi Salgia
Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA.
Jana Rolff
Experimental Pharmacology and Oncology Berlin-Buch GmbH, Robert-Roessle-Str. 10, 13125 Berlin, Germany.
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.

Notes

*Corresponding author. Email: [email protected]

Metrics & Citations

Metrics

Citations

View Options

Media

Figures

Other

Tables

Share

Information & Authors
Published In
issue cover image
Science Signaling
Volume 14|Issue 708
November 2021
Submission history
Metrics & Citations
Article Usage
Altmetrics
Export citation

Select the format you want to export the citation of this publication.

Share
Share article link

Share on social media
Get Access
Log in to view the full text

AAAS Log in

AAAS login provides access to Science for AAAS members, and access to other journals in the Science family to users who have purchased individual subscriptions.

Log in via OpenAthens.
Log in via Shibboleth.
More options

Purchase digital access to this article

Download and print this article for your personal scholarly, research, and educational use.

View Options
Tables
References

(0)eLetters

eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all. eLetters are not edited, proofread, or indexed. Please read our Terms of Service before submitting your own eLetter.

Log In to Submit a Response

No eLetters have been published for this article yet.