The PIKK-AKT connection in the DNA damage response
Abstract
DNA damage and subsequent cellular response are the basis for many cancer treatments. In this issue of Science Signaling, Liu et al. elucidate a mechanism by which cancer cells survive DNA damage induced by radiation and chemotherapy.
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Information & Authors
Information
Published In
Science Signaling
Volume 15 | Issue 715
January 2022
January 2022
Copyright
Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
This is an article distributed under the terms of the Science Journals Default License.
Submission history
Received: 29 October 2021
Accepted: 6 December 2021
Acknowledgments
We thank P. P. Roux and D. R. Plas for helpful comments on the manuscript.
Funding: This work was supported by NIH grant R01 CA240835.
Competing interests: The authors declare that they have no competing interests.
Authors
Funding Information
National Institutes of Health: R01 CA240835
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