Not just “leuko” after all: Epithelial leukotriene production in type 2 immunity
Abstract
New research shows that specialized epithelial cells (tuft cells) are major producers of lipid mediators (leukotrienes) that drive allergic inflammation and host defense against helminth parasites. (See the related Research Article by Ualiyeva et al.)
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Information & Authors
Information
Published In
Science Immunology
Volume 7 | Issue 67
January 2022
January 2022
Copyright
Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
This is an article distributed under the terms of the Science Journals Default License.
Submission history
Received: 30 November 2021
Accepted: 10 December 2021
Acknowledgments
J.E.-v.B. is supported by grants by the German Research Foundation (DFG) (FOR2599, ES 471/3-1; ES 471/2-3) and by a Helmholtz Young Investigator grant (VH-NG-1331) by the Helmholtz Initiative and Networking fund.
Author contributions: F.D.R.H. and J.E.-v.B. wrote the manuscript. F.D.R.H. and J.E.-v.B. designed the draft of the figure. J.E.-v.B. acquired funding.
Competing interests: The authors declare that they have no competing interests.
Authors
Funding Information
Epilepsy Society: FOR2599
Epilepsy Society: VH-NG-1331
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