Potent Contact Allergen in the Rubber Plant Guayule (Parthenium argentatum)
Abstract
Chemical and dermatotoxicological investigations of the natural and processed resin of the Mexican rubber plant, guayule (Parthenium argentatum), has established the presence of a sesquiterpene cinnamic acid ester (guayulin A) that is a potent elicitor of allergic contact dermatitis in experimental animals. The guayule contact allergen is comparable to the poison ivy skin allergens as an elicitor of dermatitis in sensitized guinea pigs.
References
BAER, H, DELAYED CONTACT SENSITIVITY TO CATECHOLS .3. RELATIONSHIP OF SIDE-CHAIN LENGTH TO SENSITIZING POTENCY OF CATECHOLS CHEMICALLY RELATED TO ACTIVE PRINCIPLES OF POISON IVY, JOURNAL OF IMMUNOLOGY 99: 370 (1967).
CAMPOS, E, CIENC DESARROLLO 15: 13 (1977).
EPSTEIN, W.L., POISON OAK HYPOSENSITIZATION - EVALUATION OF PURIFIED URUSHIOL, ARCHIVES OF DERMATOLOGY 109: 356 (1974).
KELCAK, G, DERMATOTOXICOLOGY PH (1977).
MAGNUSSON, B, IDENTIFICATION OF CONTACT ALLERGENS BY ANIMAL ASSAY . GUINEA PIG MAXIMIZATION TEST, JOURNAL OF INVESTIGATIVE DERMATOLOGY 52: 268 (1969).
RODRIGUEZ, E, ROLE OF SESQUITERPENE LACTONES IN CONTACT HYPERSENSITIVITY TO SOME NORTH AND SOUTH-AMERICAN SPECIES OF FEVERFEW (PARTHENIUM - COMPOSITAE), CONTACT DERMATITIS 3: 155 (1977).
ROMO, J, REVISTA LATINOAMERICANA DE QUIMICA 2: 332 (1970).
SMITH, L.M., ARCHIV FUR DERMATOLOGIE UND SYPHILIS 38: 778 (1938).
TOWERS, GHN, BIOLOGY AND CHEMISTRY OF PARTHENIUM-HYSTEROPHORUS-L, A PROBLEM WEED IN INDIA, JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH 36: 672 (1977).
Get full access to this article
View all available purchase options and get full access to this article.
Already a Subscriber?Sign In
Information & Authors
Information
Published In
Science
Volume 211 | Issue 4489
27 March 1981
27 March 1981
Copyright
© 1981.
Submission history
Published in print: 27 March 1981
Authors
Metrics & Citations
Metrics
Article Usage
Altmetrics
Citations
Export citation
Select the format you want to export the citation of this publication.
View Options
Get Access
Log in to view the full text
AAAS login provides access to Science for AAAS Members, and access to other journals in the Science family to users who have purchased individual subscriptions.
- Become a AAAS Member
- Activate your AAAS ID
- Purchase Access to Other Journals in the Science Family
- Account Help
Log in via OpenAthens.
Log in via Shibboleth.
More options
Purchase digital access to this article
Download and print this article for your personal scholarly, research, and educational use.
Buy a single issue of Science for just $15 USD.
View options
PDF format
Download this article as a PDF file
Download PDF