Genetic Mapping of the Mouse Proto-Oncogene c-sis to Chromosome 15
Abstract
The mouse homolog (c-sis) of the transforming gene of the simian sarcoma virus was mapped to chromosome 15 by the Southern blot analysis of DNA's from hamster-mouse somatic cell hybrids. Alterations in c-sis expression may thus play a role in the various murine neoplastic diseases characterized by rearrangements or duplications of chromosome 15.
References
Adams, J. M., Proceedings of the National Academy of Sciences of the United States of America 79: 6966 (1982).
Adams, J. M., Proceedings of the National Academy of Sciences of the United States of America 80: 1982 (1983).
Alitalo, K., Proceedings of the National Academy of Sciences of the United States of America 80: 1707 (1983).
BISHOP, J.M., RETROVIRUSES AND CANCER GENES, ADVANCES IN CANCER RESEARCH 37: 1 (1982).
BORNHEIM, A, CANCER GENET CYTOGEN 3: 307 (1981).
CHANG, T.D., TRISOMY OF CHROMOSOME 15 IN X-RAY-INDUCED MOUSE LEUKEMIA, PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 18: 225 (1977).
CREWS, S, MOUSE C-MYC ONCOGENE IS LOCATED ON CHROMOSOME-15 AND TRANSLOCATED TO CHROMOSOME-12 IN PLASMACYTOMAS, SCIENCE 218: 1319 (1982).
Dalla-Favera, R., Proceedings of the National Academy of Sciences of the United States of America 79: 7824 (1982).
DALLAFAVERA, R, CHROMOSOMAL LOCALIZATION OF THE HUMAN HOMOLOG (C-SIS) OF THE SIMIAN SARCOMA-VIRUS ONC GENE, SCIENCE 218: 686 (1982).
Der, C. J., Proceedings of the National Academy of Sciences of the United States of America 79: 3637 (1982).
DOFUKU, R, TRISOMY OF CHROMOSOME-15 IN SPONTANEOUS LEUKEMIA OF AKR MICE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 72: 1515 (1975).
DOOLITTLE, R.F., SIMIAN SARCOMA-VIRUS ONC GENE, V-SIS, IS DERIVED FROM THE GENE (OR GENES) ENCODING A PLATELET-DERIVED GROWTH-FACTOR, SCIENCE 221: 275 (1983).
EVA, A, CELLULAR GENES ANALOGOUS TO RETROVIRAL ONC GENES ARE TRANSCRIBED IN HUMAN-TUMOR CELLS, NATURE 295: 116 (1982).
FRANCKE, U, GENE MAPPING IN MUS-MUSCULUS BY INTERSPECIFIC CELL HYBRIDIZATION - ASSIGNMENT OF GENES FOR TRIPEPTIDASE-1 TO CHROMOSOME-10, DIPEPTIDASE-2 TO CHROMOSOME-18, ACID PHOSPHATASE-1 TO CHROMOSOME-12, AND ADENYLATE KINASE-1 TO CHROMOSOME-2, CYTOGENETICS AND CELL GENETICS 19: 57 (1977).
FRANCKE, U, CONSERVED AUTOSOMAL SYNTENIC GROUP ON MOUSE (MMU) CHROMOSOME 15 AND HUMAN (HSA) CHROMOSOME-22 - ASSIGNMENT OF A GENE FOR ARYLSULFATASE-A TO MMU 15 AND REGIONAL MAPPING OF DIA1, ARSA, AND ACO2 ON HSA 22, CYTOGENETICS AND CELL GENETICS 31: 58 (1981).
HARRIS, L.J., NON-IMMUNOGLOBULIN-ASSOCIATED DNA REARRANGEMENTS IN MOUSE PLASMACYTOMAS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79: 4175 (1982).
HAYWARD, W.S., ACTIVATION OF A CELLULAR ONC GENE BY PROMOTER INSERTION IN ALV-INDUCED LYMPHOID LEUKOSIS, NATURE 290: 475 (1981).
HOGGAN, M.D., ORGANIZATION AND STABILITY OF ENDOGENOUS XENOTROPIC MURINE LEUKEMIA-VIRUS PROVIRAL DNA IN MOUSE GENOMES, JOURNAL OF VIROLOGY 45: 473 (1983).
KOZAK, C, GENE LINKAGE ANALYSIS IN MOUSE BY SOMATIC-CELL HYBRIDIZATION - ASSIGNMENT OF ADENINE PHOSPHORIBOSYLTRANSFERASE TO CHROMOSOME-8 AND ALPHA-GALACTOSIDASE TO X-CHROMOSOME, SOMATIC CELL GENETICS 1: 371 (1975).
KOZAK, C.A., SEQUENTIAL STAINING TECHNIQUE FOR CHROMOSOMAL ANALYSIS OF INTERSPECIFIC MOUSE-HAMSTER AND MOUSE-HUMAN SOMATIC-CELL HYBRIDS, EXPERIMENTAL CELL RESEARCH 105: 109 (1977).
KOZAK, C.A., GENETIC-MAPPING OF THE ECOTROPIC VIRUS-INDUCING LOCUS AKV-2 OF THE AKR MOUSE, JOURNAL OF EXPERIMENTAL MEDICINE 152: 1419 (1980).
KOZAK, C.A., GENETIC-MAPPING OF THE ECOTROPIC MURINE LEUKEMIA VIRUS-INDUCING LOCUS OF BALB-C MOUSE TO CHROMOSOME-5, SCIENCE 204: 69 (1979).
MARK, J, IDENTIFICATION BY FLUORESCENCE OF G-CHROMOSOME LOST IN HUMAN MENINGIOMAS, HEREDITAS-GENETISKT ARKIV 71: 163 (1972).
Neel, B. G., Proceedings of the National Academy of Sciences of the United States of America 79: 7842 (1982).
OHNO, S, NON-RANDOM CHROMOSOME CHANGES INVOLVING THE IG GENE-CARRYING CHROMOSOME-12 AND CHROMOSOME-6 IN PRISTANE-INDUCED MOUSE PLASMACYTOMAS, CELL 18: 1001 (1979).
PARADA, L.F., HUMAN EJ BLADDER-CARCINOMA ONCOGENE IS HOMOLOG OF HARVEY SARCOMA-VIRUS RAS GENE, NATURE 297: 474 (1982).
PULCIANI, S, ONCOGENES IN SOLID HUMAN-TUMORS, NATURE 300: 539 (1982).
ROWLEY, J.D., CHROMOSOME-ABNORMALITIES IN MALIGNANT HEMATOLOGIC DISEASES, ADVANCES IN CANCER RESEARCH 36: 103 (1982).
ROWLEY, J.D., ONCO GEN - HUMAN ONCOGENE LOCATIONS AND CHROMOSOME-ABERRATIONS, NATURE 301: 290 (1983).
SANTOS, E, T24 HUMAN BLADDER-CARCINOMA ONCOGENE IS AN ACTIVATED FORM OF THE NORMAL HUMAN HOMOLOG OF BALB-MSV AND HARVEY-MSV TRANSFORMING GENES, NATURE 298: 343 (1982).
Schwab, M., Nature 303:497 (1983).
SHENONG, GLC, NOVEL MYC ONCOGENE RNA FROM ABORTIVE IMMUNOGLOBULIN-GENE RECOMBINATION IN MOUSE PLASMACYTOMAS, CELL 31: 443 (1982).
SOUTHERN, E.M., DETECTION OF SPECIFIC SEQUENCES AMONG DNA FRAGMENTS SEPARATED BY GEL-ELECTROPHORESIS, JOURNAL OF MOLECULAR BIOLOGY 98: 503 (1975).
SPIRA, J, NON-RANDOM CHROMOSOMAL CHANGES IN THY-1-POSITIVE AND THY-1-NEGATIVE LYMPHOMAS INDUCED BY 7,12-DIMETHYLBENZANTHRACENE IN SJL MICE, CANCER RESEARCH 40: 2609 (1980).
Swan, D. C., Proceedings of the National Academy of Sciences of the United States of America 79: 4691 (1982).
Taub, R., Proceedings of the National Academy of Sciences of the United States of America 79: 7837 (1982).
THEILEN, G.H., C-TYPE VIRUS IN TUMOR TISSUE OF A WOOLLY MONKEY (LAGOTHRIX SPP) WITH FIBROSARCOMA, JOURNAL OF THE NATIONAL CANCER INSTITUTE 47: 881 (1971).
TSICHLIS, P.N., unpublished data.
WATERFIELD, M.D., PLATELET-DERIVED GROWTH-FACTOR IS STRUCTURALLY RELATED TO THE PUTATIVE TRANSFORMING PROTEIN-P28SIS OF SIMIAN SARCOMA-VIRUS, NATURE 304: 35 (1983).
Westin, E. H., Proceedings of the National Academy of Sciences of the United States of America 79: 2490 (1982).
WIENER, F, CHROMOSOME CHANGES (TRISOMY 15) IN MURINE T-CELL LEUKEMIA INDUCED BY 7,12-DIMETHYLBENZ(A)ANTHRACENE (DMBA), INTERNATIONAL JOURNAL OF CANCER 22: 447 (1978).
WIENER, F, CHROMOSOME CHANGES (TRISOMIES-15 AND TRISOMIES-17) ASSOCIATED WITH TUMOR PROGRESSION IN LEUKEMIAS INDUCED BY RADIATION LEUKEMIA-VIRUS, JOURNAL OF THE NATIONAL CANCER INSTITUTE 61: 227 (1978).
Mushinski, J. F., Proceedings of the National Academy of Sciences of the United States of America 80: 1073 (1983).
Get full access to this article
View all available purchase options and get full access to this article.
Already a Subscriber?Sign In
Information & Authors
Information
Published In
Science
Volume 221 | Issue 4613
26 August 1983
26 August 1983
Copyright
© 1983.
Submission history
Published in print: 26 August 1983
Authors
Metrics & Citations
Metrics
Article Usage
Altmetrics
Citations
Export citation
Select the format you want to export the citation of this publication.
Cited by
- Cellular Oncogenes and Multistep Carcinogenesis, Science, 222, 4625, (771-778), (1983)./doi/10.1126/science.6356358
Loading...
View Options
Get Access
Log in to view the full text
AAAS login provides access to Science for AAAS Members, and access to other journals in the Science family to users who have purchased individual subscriptions.
- Become a AAAS Member
- Activate your AAAS ID
- Purchase Access to Other Journals in the Science Family
- Account Help
Log in via OpenAthens.
Log in via Shibboleth.
More options
Purchase digital access to this article
Download and print this article for your personal scholarly, research, and educational use.
Buy a single issue of Science for just $15 USD.
View options
PDF format
Download this article as a PDF file
Download PDF