Neuronal Activity Related to Reward Value and Motivation in Primate Frontal Cortex
Abstract
In several areas of the macaque brain, neurons fire during delayed-response tasks at a rate determined by the value of the reward expected at the end of the trial. The activity of these neurons might be related to the value of the expected reward or to the degree of motivation induced by expectation of the reward. We describe results indicating that the nature of reward-dependent activity varies across areas. Neuronal activity in orbitofrontal cortex represents the value of the expected reward, whereas neuronal activity in premotor cortex reflects the degree of motivation.
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We thank K. McCracken for technical assistance and S.-H. Lee for help in training. Supported by NIH grants MH45156, EY11831, EY08098, and P41RR03631.
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Published In
Science
Volume 304 | Issue 5668
9 April 2004
9 April 2004
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American Association for the Advancement of Science.
Submission history
Received: 3 November 2003
Accepted: 6 February 2004
Published in print: 9 April 2004
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