Neuropeptides and Peptide Hormones in Anopheles gambiae
Abstract
The African malaria mosquito, Anopheles gambiae, is specialized for rapid completion of development and reproduction. A vertebrate blood meal is required for egg production, and multiple feedings subsequently allow transmission of malaria parasites,Plasmodium spp. Regulatory peptides from 35 genes annotated from the A. gambiae genome likely coordinate these and other physiological processes. Plasmodium parasites may affect actions of newly identified insulin-like peptides, which coordinate growth and reproduction of its vector, A. gambiae, as in Drosophila melanogaster,Caenorhabditis elegans, and mammals. This genomic information provides a basis to expand understanding of hematophagy and pathogen transmission in this mosquito.
Get full access to this article
View all available purchase options and get full access to this article.
Already a Subscriber?Sign In
Supplementary Material
File (riehle1076827.sup.pdf)
REFERENCES AND NOTES
1
Klowden M. J., Arch. Insect Biochem. Physiol. 35, 491 (1997).
2
P. H. Taghert, J. A. Veenstra, Adv. Genet., in press.
3
Riehle M. A., Brown M. R., Cell Tissue Res. 308, 409 (2002).
4
Claeys I., et al., Peptides 23, 807 (2002).
5
Partridge L., Gems D., Nature Rev. Genet. 3, 165 (2002).
6
G. Macdonald, The Epidemiology and Control of Malaria (Oxford Univ. Press, London, 1957).
7
Hopwood J. A., et al., J. Exp. Biol. 204, 2773 (2001).
8
Downward J., Curr. Opin. Cell. Biol. 10, 262 (1998).
9
Beier M., et al., J. Med. Entomol. 31, 561 (1994).
10
Ozes O. N., et al., Nature 401, 82 (1999).
11
Fulton D., et al., Nature 399, 597 (1999).
12
Brown M. R., et al., J. Biol. Chem. 273, 3967 (1998).
13
M. R. Brown, C. Cao, J. Insect Sci.1.3 (2001); available online at insectscience.org/1.3.
14
Shapiro J. P., Insect Biochem. 13, 273 (1983).
15
Jenkins S. P., et al., Insect Biochem. Mol. Biol. 22, 553 (1992).
16
Veenstra J. A., et al., Peptides 18, 937 (1997).
17
Veenstra J. A., et al., Histochem. Cell Biol. 104, 337 (1995).
18
Veenstra J. A., Costes L., Peptides 20, 1145 (1999).
19
Horodyski F. M., J. Insect Physiol. 10, 917 (1996).
20
Yu M., Beyenbach K. W., J. Insect Physiol. 47, 263 (2001).
21
Veenstra J. A., et al., J. Biol. Chem. 272, 10402 (1997).
22
Clark T. M., et al., Am. J. Physiol. 274, F834 (1998).
23
Takken W., et al., J. Insect Physiol. 47, 303 (2001).
24
Stracker T. H., et al., J. Med. Entomol. 39, 331 (2002).
25
M. R. Brown, unpublished data.
26
Stanek D. M., et al., Peptides 23, 1363 (2002).
27
Garczynski S. F., et al., Peptides 23, 773 (2002).
28
Hill C. A., et al., Science 298, 176 (2002).
29
Bertenshaw G. P., et al., J. Biol. Chem. 276, 13248 (2001).
30
We thank L. Dewey and H.-Willi Honegger (Vanderbilt University) for identifying bursicon genes; P. H. Taghert (Washington University) for providing the Adv. Genet. manuscript before publication; and F. H. Collins(University of Notre Dame) and A. O. Lea for reviews. Supported by NIH grant AI33108 (M.R.B.). Financial support to the Anopheles gambiae Genome Consortium was provided by NIH grant U01 AI50687 to Celera Genomics, NIH grant U01 AI48846 to the University of Notre Dame, and French Government funds to Genoscope.
SOM text
Table S1
References
Information & Authors
Information
Published In
Science
Volume 298 | Issue 5591
4 October 2002
4 October 2002
Submission history
Received: 31 July 2002
Accepted: 10 September 2002
Published in print: 4 October 2002
Authors
Metrics & Citations
Metrics
Article Usage
Altmetrics
Citations
Export citation
Select the format you want to export the citation of this publication.
Cited by
- Prediction of neuropeptide precursors and differential expression of adipokinetic hormone/corazonin-related peptide, hugin and corazonin in the brain of malaria vector Nyssorhynchus albimanus during a Plasmodium berghei infection, Current Research in Insect Science, 1, (100014), (2021).https://doi.org/10.1016/j.cris.2021.100014
- From the Genome to the Proteome: Uncovering Peptides in the Apis Brain, Science, 314, 5799, (647-649), (2021)./doi/10.1126/science.1124128
- Crustacean neuroparsins-a mini-review, Gene, 732, (144361), (2020).https://doi.org/10.1016/j.gene.2020.144361
- Neuro-Olfactory Regulation and Salivary Actions: A Coordinated Event for Successful Blood-Feeding Behavior of Mosquitoes, Dysfunction of Olfactory System [Working Title], (2020).https://doi.org/10.5772/intechopen.80149
- The Adipokinetic Peptides in Diptera: Structure, Function, and Evolutionary Trends, Frontiers in Endocrinology, 11, (2020).https://doi.org/10.3389/fendo.2020.00153
- Peptide Hormones in the Insect Midgut, Frontiers in Physiology, 11, (2020).https://doi.org/10.3389/fphys.2020.00191
- Identification and Characterization of Neuropeptides and Their G Protein-Coupled Receptors (GPCRs) in the Cowpea Aphid Aphis craccivora, Frontiers in Endocrinology, 11, (2020).https://doi.org/10.3389/fendo.2020.00640
- Neuropeptides and peptide hormones identified in codling moth, Cydia pomonella (Lepidoptera: Tortricidae) , Archives of Insect Biochemistry and Physiology, 101, 4, (2019).https://doi.org/10.1002/arch.21587
- Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior, Progress in Neurobiology, 179, (101607), (2019).https://doi.org/10.1016/j.pneurobio.2019.02.003
- Evolutionary trends of neuropeptide signaling in beetles - A comparative analysis of Coleopteran transcriptomic and genomic data, Insect Biochemistry and Molecular Biology, 114, (103227), (2019).https://doi.org/10.1016/j.ibmb.2019.103227
Loading...
View Options
Get Access
Log in to view the full text
AAAS login provides access to Science for AAAS Members, and access to other journals in the Science family to users who have purchased individual subscriptions.
- Become a AAAS Member
- Activate your AAAS ID
- Purchase Access to Other Journals in the Science Family
- Account Help
Log in via OpenAthens.
Log in via Shibboleth.
More options
Purchase digital access to this article
Download and print this article for your personal scholarly, research, and educational use.
Buy a single issue of Science for just $15 USD.
View options
PDF format
Download this article as a PDF file
Download PDF