Blogs
As robotics and artificial intelligence (AI) become more ingrained in everyday life, we must make sure that the technology is free from bias. Robots are typically given some level of autonomy through AI. For example, patients must trust assistive robots to deliver health care, and occupants must trust autonomous vehicles to make the safe decisions. Because bias undermines trust and perpetuates inj
Messing around with cytokine signaling is a very large business indeed (because it's a very large area of cell biology as well). We've heard a lot about it during the pandemic, for example, with the too-vigorous immune response that gets many severely infected people into trouble. And that illustrates the balance in modulating such signaling: it's absolutely necessary for the immune pathways to fu
I'd like to recommend this excellent article by Olivia Goodhill at Stat for people wondering how you keep a vaccine up-to-date given the constant emergence of viral variants. It's an exclusive look at Pfizer's Pearl River site, which has that important but extremely demanding assignment, and it's a look at what really is the state of the art in commercial vaccine development. The usual warnings ab
Editor's Blog
As robotics and artificial intelligence (AI) become more ingrained in everyday life, we must make sure that the technology is free from bias. Robots are typically given some level of autonomy through AI. For example, patients must trust assistive robots to deliver health care, and occupants must trust autonomous vehicles to make the safe decisions. Because bias undermines trust and perpetuates inj
Devin Swiner is a senior scientist at Merck. She received her PhD from The Ohio State University and is now the leader of #BlackChemistsWeek2021, which kicks off next week (8 to 14 August). I talked with her about her advocacy and hopes for this year’s event.
Holden Thorp: Thank you for all you’re doing. I’d like to start by hearing a little bit about your journey as a scien
Devin Swiner is a senior scientist at Merck. She received her PhD from The Ohio State University and is now the leader of #BlackChemistsWeek2021, which kicks off next week (8 to 14 August). I talked with her about her advocacy and hopes for this year’s event.
Holden Thorp: Thank you for all you're doing. I'd like to start by hearing a little bit about your journey as a scientist. How you dec
It’s been just over 5 years since then Editor-in-Chief Marcia McNutt published an editorial committing Science to adoption of the Transparency and Openness Promotion (TOP) framework to facilitate reproduction of research published in the journal. This was a multifaceted commitment, but a big component involved directing authors to repositories for permanent, accessible archiving of the data and co
Patrick Radden Keefe’s new book Empire of Pain chronicles the history of the Sackler family and Purdue Pharma, which played a destructive role in the opioid crisis. While Keefe rightfully places much of the blame on the Sackler family, I was curious about why scientists inside or outside the company didn’t do more to stop the crisis sooner. Given his detailed reporting, I thought he might have som
Wherever science and race intersect, vexing questions surface. How does science conceptualize racial and human differences? How have different sciences produced ideas about race, and how have these ideas contributed to progressive social reform and, alternatively, to reactionary, oppressive, and even racist practices? What is the history of participation of ethnic minorities in science, and of the
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Visuals
“I work with scientists because otherwise it would just be art for no reason,” explains photographic artist Mandy Barker. Her award-winning plastic pollution photography has been published by a long list of organizations including Time magazine, Vogue, and CNN in 50 different countries.
Mandy Barker is a photographic artist who calls attention to plastic pollution.KNUT KOIVISTO
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Cauliflower isn’t something I usually get excited about. But the 12 cauliflowers arriving today from California were different. These were Romanesco—a special kind.
One of the joys of working as a producer is chatting one-on-one with people as they share fascinating knowledge and stories, not to mention “playing” (let’s call it as it is) with high-tech equipment. Last year, the COVID-19 pandemic swooped in and ruined that fun, to say the least. To ensure safety, Science and many other media outlets began conducting interviews over Zoom rather than in person. They were gritty: something like dispatches from the resistance in a postapocalyptic, dystopian film.
Three illustrations I have art directed this year all relate to pandemic life. Each presented the challenge of showing life on a screen in a new way. Each illustration merged many different ideas, requiring a solution showing multiple elements and themes coexisting in one larger scene. This Letters section asked readers the following question: “What new word or phrase would you add to the dictionary to help scientists explain the events of 2020 to future generations?” Our readers gave answers that ranged from clever to poignant.
In the Pipeline
Messing around with cytokine signaling is a very large business indeed (because it's a very large area of cell biology as well). We've heard a lot about it during the pandemic, for example, with the too-vigorous immune response that gets many severely infected people into trouble. And that illustrates the balance in modulating such signaling: it's absolutely necessary for the immune pathways to fu
I'd like to recommend this excellent article by Olivia Goodhill at Stat for people wondering how you keep a vaccine up-to-date given the constant emergence of viral variants. It's an exclusive look at Pfizer's Pearl River site, which has that important but extremely demanding assignment, and it's a look at what really is the state of the art in commercial vaccine development. The usual warnings ab
It’s comparatively old news by now, since the blog has been on “upgrade hiatus”. But we’ve recently seen two high-profile departures from prominent positions in the biomedical field due to allegations of sexual harassment.
One of those is Aubrey de Grey, the (former) CSO of the SENS Research Foundation. That’s an acronym for “strategies for engineered negligible
OK, as things are lifting off around here, I wanted to address some common questions that have come in. First off, there will indeed be an RSS feed. It's being trouble-shot now, but RSS will indeed continue. Second, the old comments for all the previous posts are indeed going to be carried over, and that's in progress as well. There are. . .quite a few of them, so it may take a bit more time, but
So this will be the last post here until sometime next week, as the entire Science site does a behind-the-scenes changeover to a new publishing platform. Redirects from all old links to the previous posts should be in place on the re-emergence, along with a new look to the blog, a new commenting system, and new blog-writing software back here on this end. Here's hoping everything goes as planned, and I'll see everyone on the other side.
Here's another post that I will regret writing, but a great many people have asked me about a new preprint that brings up the possibility of antibody-dependent enhancement with the current vaccines and the Delta variant. To be frank, some of the people promoting this seem to be rooting for the virus, just so long as it humiliates their enemies and proves their own positions to be correct, but there are a lot of honestly worried people out there who are wondering what this paper means. So let's look at it, with an eye to lessons for evaluating such papers in general.The authors are building on another recent paper (Li et al.) on neutralizing and non-neutralizing antibodies against the current coronvirus. The preprint version of that one came out in February, and the final version went online in June.










