Given the evidence for a hyperactive platelet phenotype in COVID-19, we investigated
effector cell properties of COVID-19 platelets on endothelial cells (ECs). Integration
of EC and platelet RNA sequencing revealed that platelet-released factors in COVID-...
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound dysregulation
of the innate immune system. This knowledge has emerged from the large body of single-cell
omics studies of patients with COVID-19, which have provided one of the ...
Excessive complement activation contributes to lung disease and adverse patient outcomes
in COVID-19 (see the related research articles by Yan et al. and Ma et al.).
Severe coronavirus disease 2019 (COVID-19) pneumonia survivors often exhibit long-term
pulmonary sequelae, but the underlying mechanisms or associated local and systemic
immune correlates are not known. Here, we have performed high-dimensional ...
In-person schooling has proved contentious and difficult to study throughout the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Data from a massive
online survey in the United States indicate an increased risk of COVID-19–related
...
A new high-throughput screening technique detected autoantibodies in COVID-19 patients
specific for many different immunomodulatory extracellular and cell surface proteins,
several of which were associated with disease severity and clinical outcomes.
The stalling of COVID-19 vaccination rates threatens public health. To increase vaccination
rates, governments across the world are considering the use of monetary incentives.
Here we present evidence about the effect of guaranteed payments on COVID-19 ...